Background: Pre-eclampsia is responsible for significant maternal and perinatal morbidity and mortality worldwide. Serum LDH level is a useful biomarker to detect the extent of cellular injury in women with pre- eclampsia. Thus it can be used to predict prognosis for both mother and fetus and timely management.

Materials & Methods: This was a hospital based analytical observational study in department of Obstetrics and Gynaecology, SMS Medical College, Jaipur from April 2021 to August 2022 on 250 women with ≥28 weeks gestation with pre-eclampsia.

Results: Mean serum LDH levels were higher in female with pre-eclampsia with severe features as compared to female with pre-eclampsia without severe features(p <0.0001). Higher serum LDH levels were found to be associated with poor fetomaternal outcome.

Conclusion: S.LDH levels can be used to predict the prognosis of pre-eclampsia. Women with pre-eclampsia with raised serum LDH levels mandate close monitoring, prompt and correct management to reduce fetomaternal morbidity and mortality.